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2019

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08

Why cancer stem cells are the culprit of tumor recurrence and metastasis? -- "Huaier Granule" solves the problem of cancer stem cells


Our body is a kingdom of 40 trillion to 60 trillion cells, extremely complex and highly ordered. Modern medical research has confirmed that all cells in the human body are derived from the replication, reproduction and differentiation of stem cells, which are the well-deserved "source of life".

So, what exactly is a stem cell? The "stem" in stem cells means "trunk" and "origin. Stem cells can be divided into "totipotent stem cells", "pluripotent stem cells" and "unipotent stem cells" three categories. If the human body is compared to a tree, the seeds buried deep in the earth are "omnipotent stem cells", which can differentiate into a complete human body, just as the seeds can develop into a towering tree. For example, the combination of human sperm and egg can give birth to new life, and this fertilized egg is a seed, a kind of omnipotent stem cell. The trunk of a big tree can be compared to "pluripotent stem cells", which can differentiate into human nerve cells, myocardial cells, liver cells, muscle cells and other multi-system functional cells, just like a tree trunk can grow lush branches, leaves and fruits. The branches at the end of the tree can be compared to "unipotent stem cells". This kind of unipotent stem cells are also called specialized stem cells, which can only differentiate into one type or two closely related types of cells. For example, hematopoietic stem cells are a kind of unipotent stem cells, which can only differentiate into red blood cells, white blood cells, platelets and so on in the blood system.

In addition to the birth of new life, normal stem cells are carried out by a variety of stem cells, which is an important guarantee for the maintenance of life and health. So what is the difference between normal stem cells and cancer stem cells? Normal stem cells repair and improve the tissues and organs of life in an orderly and controllable manner according to the needs of life movement in various periods, which is a balanced, orderly and strictly controllable process. Cancer stem cells are out of control, in a state of uncontrolled and unlimited proliferation. It can be said that they are stem cells that are immortal, continue to divide, and lose their normal differentiation ability.

Cancer stem cells, which are characterized by out-of-control proliferation and abnormal differentiation, transfer to a variety of human tissues to form heterogeneous tumors and destroy the function of normal tissues and organs. For example, breast cancer, because breast cancer stem cells continue to proliferate indefinitely, space-occupying lesions will be formed, which will oppress and invade other normal tissues. In this process, a large amount of nutrition is needed to ensure the survival of tumor cells, and at the same time various toxic metabolic substances are released., Resulting in a healthy person to lose weight and various pathological symptoms, and eventually take life.

Some people will say, we have seen some patients with liver cancer after radical resection, even after the entire liver is replaced, why does the liver cancer relapse and metastasize after a period of time? This is because the general tumor cells do not have the ability to proliferate indefinitely, but have a strong vitality, and we can currently remove and resolve the tumor cells through surgery, chemoradiation, targeted drugs, and genetic drugs. However, the tumor stem cells that produce tumor cells are extremely cunning. They are usually in a dormant, quiescent, latent, and poorly differentiated state. No matter how clever surgery can completely remove them, traditional radiotherapy and chemotherapy cannot completely kill them, and face a variety of targets. With the pursuit of drugs, cancer stem cells will find a way to find another pathway to "escape" and stay in the body. Therefore, although cancer stem cells account for only a very small number of all tumor cells, they play a key role in tumor survival, proliferation, metastasis and recurrence: on the one hand, cancer stem cells strengthen the vitality of tumor cell population through self-renewal and unlimited proliferation; on the other hand, the movement and migration ability of cancer stem cells make it possible for tumor cells to metastasize. This is the fundamental reason why tumors often relapse and metastasize after a period of time after removing and destroying most of the ordinary tumor cells regular treatment. Therefore, the medical community generally believes that cancer stem cells are the root cause of tumor formation, development and deterioration, and the culprit of tumor recurrence and metastasis.

"Huaier granule" is a drug that has been proved by the medical community to solve cancer stem cells. Except for "Huaier granule", no other drugs have been found in the world, including the latest targeted drugs and gene drugs. Judging from the latest research at home and abroad, "Huaier particles" solve the problem of tumor stem cells, which can be expressed in two forms: one is to make tumor stem cells apoptosis (death); the other is to transform tumor stem cells into normal stem cells and generate normal tissue. This is the only drug in the world that has been proven to have this feature. Tumor disease, like hypertension and diabetes, is a chronic disease, so to prevent tumor recurrence and metastasis, long-term use of "Huaier Granules" is a correct choice.